2025 Drug Overdose Integrated Epidemiology Profile (DOIEP)
The DOEIP is a comprehensive annual report that characterizes the epidemiology of drug overdose in Cuyahoga County. Drawing on multiple data systems, the report examines overdose mortality and morbidity across sociodemographic and geographic populations, monitors trends over time, and identifies risk and protective factors associated with drug overdose. These findings provide actionable public health data to guide the planning, implementation, and evaluation of overdose prevention initiatives.
Key Findings:
- In 2024, 40% of unintentional deaths in Cuyahoga County were due to drug overdose
- There were 353 unintentional drug overdose deaths among residents in 2024, a decease of over 35% from 2023
- Non-Hispanic Black males continue to experience the highest rate of unintentional drug overdose deaths
- 73% of all unintentional drug overdose deaths in 2024 involved fentanyl and/or fentanyl analogues
- There were 2,708 emergency department (ED) visits for suspected drug overdose in 2024, representing a decreasing trend since 2017
- There were 2,744 naloxone doses administered by emergency medical services (EMS) in 2024, representing a decreasing trend since 2019
- ZIP Code 44109 experienced the highest rates of both ED visits due to suspected drug overdose and unintentional drug overdose deaths
Acknowledgement:
The DOIEP was made possible through the Overdose Data to Action: Limiting Overdose through Collaborative Actions in Localities grant from the Centers for Disease Control and Prevention. The Population Health service area leads Cuyahoga County’s OD2A program and Epidemiology, Surveillance, & Informatics leads the overdose surveillance strategy.
More overdose data insights are available here: https://ccbh.net/overdose-data-dashboard/


